RELATIVE ENERGY CALIBRATION OF THE TJNAF HALL-B PHOTON TAGGER AND INVESTIGATION OF LIMITATIONS OF THE PHOTON TAGGING TECHNIQUE

In this work we report on two sets of measurements involving the Hall-B photon tagging system of the Tomas Jefferson National Accelerator Facility. The relative energy calibration of the tagging counters was performed by using the PrimEx pair spectrometer and a series of high position resolution micro-strip detectors. The photon energies were determined by forming coincidence between the tagger and the e+ e- pairs for several values of the pair spectrometer magnetic field between 0.36T to 1.9T (total of 180 fields). The second set of measurements, collected in conjunction with the Fall 2004 PrimEx run, investigated inherent limitations on the photon tagging technique. We report for the first time an experimental signature for these effects

Electroproduction of Λ\Lambda(1405)

The electroproduction of $K^+ \Lambda$ (1405) was studied by analyzing the E1F data set collected in Hall B at Jefferson Lab. The analysis utilized the decay channel $\Sigma^+ \pi^-$ of the $\Lambda$ (1405) and $p \pi^0$ of the $\Sigma^+$. Simulations of background, $\Lambda$ (1405) and $\Lambda$ (1520) production according to PDG values were performed by using standard CLAS analysis tools adapted for the E1F run. Fits of the acceptance-corrected simulations were made to the acceptance-corrected data to determine contributions from signal and background processes. The line shape of $\Lambda$ (1405) varies with the four momentum transfer, $Q^2$, and does not match the line shape based on PDG resonance parameters. It corresponds approximately to predictions of a recent two-pole meson-baryon picture of this state.Comment: 4 pages, 6 figures, Contribution to the Proceedings of "NSTAR2011 - The 8th International Workshop on the Physics of Excited Nucleons," Thomas Jefferson National Accelerator Facility, Newport News, Virginia USA, 17-20 May 201

Automated deep learning segmentation of high-resolution 7 T postmortem MRI for quantitative analysis of structure-pathology correlations in neurodegenerative diseases

Postmortem MRI allows brain anatomy to be examined at high resolution and to link pathology measures with morphometric measurements. However, automated segmentation methods for brain mapping in postmortem MRI are not well developed, primarily due to limited availability of labeled datasets, and heterogeneity in scanner hardware and acquisition protocols. In this work, we present a high resolution of 135 postmortem human brain tissue specimens imaged at 0.3 mm$^{3}$ isotropic using a T2w sequence on a 7T whole-body MRI scanner. We developed a deep learning pipeline to segment the cortical mantle by benchmarking the performance of nine deep neural architectures, followed by post-hoc topological correction. We then segment four subcortical structures (caudate, putamen, globus pallidus, and thalamus), white matter hyperintensities, and the normal appearing white matter. We show generalizing capabilities across whole brain hemispheres in different specimens, and also on unseen images acquired at 0.28 mm^3 and 0.16 mm^3 isotropic T2*w FLASH sequence at 7T. We then compute localized cortical thickness and volumetric measurements across key regions, and link them with semi-quantitative neuropathological ratings. Our code, Jupyter notebooks, and the containerized executables are publicly available at: https://pulkit-khandelwal.github.io/exvivo-brain-upennComment: Preprint submitted to NeuroImage Project website: https://pulkit-khandelwal.github.io/exvivo-brain-upen

Measurement of the induced polarization of Λ(1116) in kaon electroproduction with CLAS

The CLAS Collaboration is using the p(e, e&feet; K+ p)π- reaction to perform a measurement of the induced polarization of the electroproduced Λ(1116). The parity-violating weak decay of the Λ into pπ- (64%) allows extraction of the recoil polarization of the Λ. The present study uses the CEBAF Large Acceptance Spectrometer (CLAS) to detect the scattered electron, the kaon, and the decay proton. CLAS allows for a large kinematic acceptance in Q2 (0.8 ≤ Q2 ≤ 3.5 GeV2 ), W (1.6 ≤ W ≤ 3.0 GeV), as well as the kaon scattering angle. In this experiment a 5.499 GeV electron beam was incident upon an unpolarized liquid-hydrogen target. The goal is to map out the kinematic dependencies for this polarization observable to provide new constraints for theoretical models of the electromagnetic production of kaon-hyperon final states. Along with previously published photo- and electroproduction cross sections and polarization observables from CLAS, SAPHIR, and GRAAL, these data are needed in a coupled-channel analysis to identify previously unobserved s-channel resonances